Endocrine Abstracts

Background: Depressive mood consequent to hypothyroidism can be reversed with levothyroxine (LT4) replacement therapy. However, it is unclear whether increasing LT4 dose confers additional mood benefits.Methods: This was a single-blind before-and-after study of 26 patients with hypothyroidism who were aged 65 years or older and undergoing LT4 replacement therapy. Geriatric Depression Scale (GDS-K) and Hyperthyroid Symptom Scale (HSS-K) were assessed at b...